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Oprah Winfrey is announcing she'll end her widely popular television show in 2011. She's been part of our lives for 25 years. So we want to know, what's your favorite Oprah moment?

Leave us a comment. We’ll share some of them on air in the CNN Newsroom, 11am – 1pm ET.

Tennis superstar Andre Agassi says he used the drug crystal meth in 1997, before spiraling to 141st in world tennis rankings later that year. The stunning admission comes in an upcoming autobiography.
In a excerpt published in the Times of London, Agassi says he lied to tennis officials after failing a drug test, saying he accidentally drank from an assistant's soda spiked with the highly addictive drug. They believed him.

Agassi is not the first star athlete/role model to abuse dangerous drugs and lie about it - and certainly won't be the last. We want to know what you think. Are you shocked by the news, or is it just another celebrity-gone-bad story? Share your thoughts and comments.

The debate has already begun for Sen. Baucus’ health reform plan. Do you plan to read it? Or will you rely on the media debate to shape your view of the plan?

I want to hear from you. Send me your thoughts at cnn.com/tony.
Here's the link to the Baucus plan so you can find it quickly and read it during your free time this weekend.

http://www.cnn.com/SPECIALS/2009/health.care/

We're focusing on Health Care!
Congress is working on several bills for health care reform.
We want to hear from you.
What do you have to have in your health care plan?
Should the government mandate health coverage?
Do you support a public option?
Who should pay?
Send me your thoughts!

AIG is set to pay bonuses next week that were promised last year, and the insurance giant is asking the government for its blessing.
The Bonuses paid to executives of companies that received bailout money such as Bank of America, Citgroup and AIG caused a firestorm earlier this year.
These latest bonuses are supposed to be contingent on certain targets related to AIG’s restructuring. Does that make it okay? Remember, it’s your tax dollars propping this company up.
Tell us what you think. Should the Obama administration give its blessing to this new round of AIG executive bonuses?

Rep. Peter King says he’s appealing to real people when he says the media should focus more on the men and women of the U.S. military than on Michael Jackson. He calls Jackson a child molester and pedophile. It’s easy to argue the media coverage of Michael Jackson has been excessive, but is it fair to attack a dead man who can’t defend himself? Share your thoughts: do you agree with Rep. Peter King? Or are his remarks out of line?

A federal judge has approved General Motors’ plan to emerge from bankruptcy. Under the restructuring plan, the Detroit-based automaker creates a new company and sheds crushing debt and expensive contracts. We want to hear from you. What kind of chance do you give the new GM? Will it ever be back on top?

A legislative aide for Tennessee state senator Diane Black (R-Gallatin) recently sent on an e-mail with this picture. The aide, Sherri Goforth says, “I went on the wrong e-mail and I inadvertently hit the wrong button.” Her boss gave her a reprimand, but some in the Tennessee black causus say Goforth should be fired. Tell us what you think.

As part of our week-long examination of the nation’s health care, Senior Medical Correspondent Elizabeth Cohen looks into racial and gender disparities. Do white people get better health care than minorities? Do men get better health care than women? How and why does this happen? Join Tony and Elizabeth today at 11am ET, and share your comments and stories here.

From CNN Senior Medical Correspondent Elizabeth Cohen

All this week, Tony Harris and I will be taking a look at the American health care system, what's broken, what works and what needs to be done to insure the 46 million Americans who don't have health insurance. Step one: figuring out the why health care in Miami is more than twice as expensive as it is in Portland, Oregon. Tony and I will break it down. In meantime, check out this interactive map from the Dartmouth Institute for Health Policy and Clinical Practice to see how much health care costs where you live.